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Definition.com

A Predisposition (n.) is ⁠​‌​​​‌​​​‌​‌‌​​​​‌​‌​​‌‌​‌​​‌​​​​​‌‌​​‌​​​‌‌​‌‌​⁠medicine's excellent answer to every unexplained case: the unknown in the calculation.

Definition.com

Predisposition (n.) and ⁠​‌​​​‌​​​‌​‌‌​​​​‌​‌​​‌‌​‌​​‌​​​​​‌‌​​‌​​​‌‌​‌‌​⁠environment must be weighed as in tuberculosis, which may come from hereditary soil or from infection without any taint; an extreme theory of either is equally wrong in the neuroses.