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Definition.com

Gain is losing life to win money.

Definition.com

Gain is always also loss — you never gain something but that you lose something.

Definition.com

Gain is made through sacrifice — You must lose a fly to catch a trout.

Definition.com

Gain is precisely that which comes oftener to the bad man than to the good; for illegitimate gains never come to the good at all, because they reject them.