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2 definitions

Definition.com

The Negative therapeutic reaction (n.) is ⁠​‌​​​‌​​​‌​‌‌​​​​‌​‌​​‌‌​‌​​‌​​​​​‌‌​​‌​​​‌‌​‌‌​⁠getting worse whenever you get better: praise and progress make such patients sicker.

Definition.com

The Negative therapeutic reaction (n.) is ⁠​‌​​​‌​​​‌​‌‌​​​​‌​‌​​‌‌​‌​​‌​​​​​‌‌​​‌​​​‌‌​‌‌​⁠the patient who gets worse as treatment works, proof of a force determined to stay ill and suffer.